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Welcome Sarah & Malek!

9/30/2020

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We're delighted to welcome two IGP students to the lab for the second rotation. Sarah and Malek will join us to learn cryoEM and X-ray methods. So glad you both wanted to join us!
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Rotation projects 2020-21

7/17/2020

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We are recruiting! Please get in touch if you are interested in rotating. The lab is a great place to train. We have an awesome and experienced lab manager (Amy), two excellent postdocs (John & Mintu), and two talented senior graduate students (Betty & Natalie) to support you. We use a variety of techniques and approaches in the lab to answer fundamental questions about cell biology and human brain disease. We have multiple projects focused around important human protein complexes (COPI, retromer, AP4, AP5).
  1. Protein expression & purification (bacteria & mammalian cells)
  2. Biochemistry: pulldown assays & calorimetry
  3. Crystallization & X-ray crystallography, including small molecules/drugs
  4. Single particle cryo-EM
  5. Imaging
  6. Computational projects to predict protein structures and disease pathology (with Capra lab, UCSF)
If you’re interested, please email resume/CV and brief background summary (science courses, research interests) to Lauren. We’ll then set up a time to meet. We look forward to hearing from you!
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Welcome new graduate students

7/14/2020

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The Jackson lab is recruiting. Check out our virtual lab introduction here. 

Please contact us if you are interested in rotating. We'd love to have you!
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John appointed to T32 training grant

4/22/2020

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Congratulations to our fabulous postdoc, John, for being appointed to the competitive Vanderbilt Functional Neurogenomics training grant. We look forward to his exciting plans and studies to be focused on adaptor protein complexes. 
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New paper out at Protein Science

4/17/2020

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Congratulations to John, Carli, and our collaborators for a new paper out in the Cellular Dynamics special issue of Protein Science. It was fun to learn some new approaches to thinking about AP-4 structure in tandem with evolutionary and disease data.

​Check out the paper here
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Retromer featured on Structure cover

4/9/2020

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Congratulations to Amy and all co-authors for a beautiful cover at Structure. Check out final published version here and the cover image here. Thanks to the Munson lab (UMass Medical School) for writing a Preview article featuring our structures!
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Retromer paper online

2/6/2020

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Check it out at: ​https://www.cell.com/structure/fulltext/S0969-2126(20)30009-5
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Retromer paper accepted!

2/5/2020

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Congratulations to Amy, Betty, and all of our fantastic collaborators. Our first single particle cryoEM structure paper was accepted at Structure. Proud of the lab for taking the plunge (terrible pun!) into a new area of structural biology. We look forward to many more single particle structures!
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Lauren wins Nordhaus teaching award from A&S

1/13/2020

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In December, Lauren won the Nordhaus award for excellence in undergraduate teaching based on her contributions to Biochemistry. It was a wonderful surprise to end the year! Check it out here: https://as.vanderbilt.edu/news/2019/12/10/2019-faculty-awards/

You can read more about history of the award here:
https://as.vanderbilt.edu/faculty/awards.php
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Welcome Melissa!

8/20/2019

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We are delighted to welcome a new undergraduate, Melissa,  to the lab this semester. Melissa is an MCB major on the pre-med track who is broadly interested in trafficking proteins and how pathogens attack cells. 
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