Please get in touch with Lauren if you are interested in rotating. The lab is a great place to train. We have an awesome lab manager (Amy), an experienced research assistant professor (Mintu), and two talented graduate students (Natalie & Cameron) to support you. We use a variety of techniques and approaches to answer fundamental questions about cell biology and human brain disease. We have multiple projects focused around important human protein complexes (retromer & sorting nexins, AP4, COPI). Options include:

1. Protein expression & purification (bacteria & mammalian cells)
2. Biochemistry: pulldown assays & calorimetry
3. Crystallization & X-ray crystallography, including small molecules/drugs
4. Single particle cryo-EM and cryo-ET
5. Imaging
6. Computational projects (AlphaFold modeling)

If you’re interested, please email your resume/CV and brief background summary (science courses, research interests) to Lauren. We’ll then set up a time to meet. We look forward to hearing from you!

The chair (Brandt) came by on Friday afternoon to tell us officially that Lauren will be promoted to associate professor with tenure. The lab had a little gift squirreled away, and fortunately Lauren also had a spare bottle of bubbly, because our NIH MIRA/R35 has also been renewed. A great week for the Jackson lab!

We are absolutely delighted to welcome a new graduate student, Cameron Cohen, into the Jackson lab. Cameron joins us from IGP after completing her bachelor's degree in Biology at Emory. 

Many thanks to NIGMS for featuring the lab on their Biomedical Beat blog this week. Lauren shared a little back about her undergraduate research background and perspective on science. The blog features a fantastic cryo-EM image from Amy Kendall, as well as the nerdiest picture of Lauren known to exist.

Dr. Xie has just accepted a postdoctoral position at Eli Lilly, based in San Diego. Very proud of Betty's many accomplishments in the lab and beyond. Can't wait to visit her in SD.

Congratulations to Mintu for publishing his paper identifying a biochemical link between the SNX-BARs, SNX1/SNX2, and SNX27. Article available online here

Delighted to welcome Cameron Cohen to the lab for our first IGP rotation of the year. 

Betty defended her thesis with flying colors in August. Very proud of her hard work over all these years, including crazy COVID times. Can't wait to see what she does next!

We're delighted to welcome two IGP students to the lab for the second rotation. Sarah and Malek will join us to learn cryoEM and X-ray methods. So glad you both wanted to join us!