Publications
.Jackson Lab
28. 28. Wallace NS, Gadbery JE, Cohen CI, Kendall AK, and Jackson LP. Tepsin binds LC3B to promote ATG9A trafficking and delivery. Molecular Biology of the Cell 2024 Feb 21:mbcE23090359T. doi: 10.1091/mbc.E23-09-0359-T.
27. Xie B, Guillem C, Date SS, Jung C, Kendall AK, Best J, Graham TR, and Jackson LP. An interaction between b’eta-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling. J Cell Biology 2023 Apr 3;222(4):e202008061.
26. Pembridge O, Wallace NS, Clements TP, Jackson LP. AP-4 loss in CRISPR-edited zebrafish affects early embryo development. Adv Biol Regul. 2023 Jan;87:100945
25. Kendall AK, Chandra M, Xie B, Wan W, and Jackson LP. Improved retromer cryo-EM structures reveal a new assembly interface. In revision. J Biological Chemistry 2022 Nov;298(11):102523.
24. Date SS, Xu P, Hepowit NL, Diab NS, Best J, Xie B, Jiale Du, Strieter ER, Jackson LP, MacGurn JA, Graham TR. Ubiquitination drives COPI priming and Golgi SNARE localization. eLife. 2022 Jul 29;11:e80911.
23. Chandra M, Collins BM, and Jackson LP. Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus. (2022). Advances in Biological Regulation 83:100842.
22. Kai-En Chen, Qian Guo, Yi Cui, Amy K. Kendall, Joanna Sacharz, Timothy A. Hill, Ryan J. Hall, Suzanne J. Norwood, Natalya Leneva, Boyang Xie, Zhe Yang, Rajesh Ghai, Hiroaki Suga, David Fairlie, David A. Stroud, Jackson LP, Rohan D. Teasdale, Toby Passioura, Brett M. Collins. (2020). De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex. Science Advances, 2021 Dec 3;7(49):eabg4007.
21. Chandra M†, Kendall AK, and Jackson LP†. (2021). Toward understanding the molecular role of SNX27/retromer in human health and disease. Frontiers Cell & Developmental Biology 9:642378. (†corresponding authors)
20. Xie B, Jung C, Chandra M, Engel A, Kendall AK, and Jackson LP. (2021). The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats. Advances in Biological Regulation 79:100781.
19. Snider CE, Chandra M, McDonald NA, Willet WH, Collier SE, Ohi MD, Jackson LP, and Gould KL. (2020). Opposite faces of the Cdc15 F-BAR domain create a membrane platform that coordinates cytoskeletal and signaling components during cytokinesis. Cell Reports 33 (12): 108526.
19. Crawley-Snowdon H, Yang J-C, Zaccai NR, Davis L, Wartosch L, Herman EK, Bright NA, Swarbrick JS, Collins BM, Jackson LP, Seaman MNJS, Luzio JP, Dacks JB†, Neuhaus D†, Owen DJ†. (2020). Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. Nature Communications. 11(1): 5031. (†joint corresponding authors)
18. Chandra M, Kendall AK, and Jackson LP. (2020). Unveiling the cryo-EM structure of Retromer. Biochemical Society Transactions 48 (5): 2261-72.
17. Gadbery JE*, Abraham A*, Needle C, Moth C, Sheehan J, Capra JA, Jackson LP. (2020). Integrating Structural and Evolutionary Data to Interpret Genetic Variation and Pathogenicity in Adaptor Protein Complex 4 (AP-4). Protein Sci 29 (6): 1535-1549. (*joint first authors)
16. Kendall AK, Xie B, Xu P, Wang J, Burcham R, Frazier MN, Binshtein E, Wei H, Graham TR, Nakagawa T, Jackson LP. (2020). Mammalian retromer is an adaptable scaffold for cargo sorting from endosomes. Structure 28: 393-405. (Featured on cover and in Preview article.)
15. Davies AK, Itzhak DN, Edgar JR, Archuleta TL, Hirst J, Jackson LP, Robinson MS, and Borner GHH. (2018). AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. Nature Comm 9: 3958.
14. Xu P, Hankins HM, Macdonald C, Erlinger SJ, Frazier MN, Diab NS, Piper RC, Jackson LP, MacGurn JA, and Graham TR. (2017). COPI mediates recycling of an exocytic SNARE from endosomes by recognition of a ubiquitin sorting signal. eLife 2017; 6:e28342. DOI:10.7554/eLife.28342.
13. Archuleta TA, Frazier MN, Monken A, Kendall AK, Harp J, McCoy AJ, Creanza N, and Jackson LP. (2017). Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin. Traffic 18: 590-603.
12. Frazier MN and Jackson LP. (2017). Watching real-time endocytosis in living cells. J Cell Biology 216, 9-11.
11. Frazier MN, Davies AK, Voehler M, Kendall AK, Borner GH, Chazin WJ, Robinson MS, and Jackson LP. (2016). Molecular basis for the interaction between Adaptor Protein Complex 4 (AP4) b4 and its accessory protein, tepsin. Traffic 17, 400-415.
10. Jackson LP. (2014). Structure and mechanism of COPI vesicle biogenesis. Curr Opin Cell Biol 29C, 67-73.
Postdoctoral, graduate, & undergraduate work
9. Hesketh GG*, Pérez-Dorado I*, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MN, Luzio JP, Owen DJ. (2014). VARP is Recruited Onto Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface. Dev Cell 29, 591-606. (*joint first authors)
8. Jackson LP†, Lewis M, Kent HM, Edeling MA, Evans PR, Duden R, and Owen DJ†. (2012). Molecular basis for recognition of dilysine trafficking motifs by COPI. Dev Cell 23, 1-8. (†corresponding authors)
7. Jackson LP†, Kümmel D†, Reinisch K, and Owen DJ. (2012). Structures and mechanisms of vesicle coat components and multisubunit tethering complexes. Curr Opin Cell Biol 24, 475-483. (†corresponding authors)
6. Borner GHH, Antrobus R, Hirst J, Bhumbra GS, Kozik P, Jackson LP, Sahlender DA, and Robinson MS. (2012). Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles. J Cell Biol 197, 141-60.
5. Jackson LP*, Kelly BT*, McCoy, AJ, Gaffry, T, James LC, Collins BM, Höning S, Evans PR, Owen DJ. (2010). A large scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex. Cell 141, 1220-29. (*joint first authors)
4. Pryor PR, Jackson LP, Gray SR, Edeling MA, Thompson A, Sanderson CM, Evans PR, Owen DJ, Luzio JP. (2008). Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb. Cell 134, 817-27.
3. Parker L, Kendall A, Berger, PH, Shiel, PJ, and Stubbs, G. (2005). Wheat streak mosaic virus— Structural parameters for a Potyvirus. Virology 340, 64-69 (featured on cover)
2. Stubbs G, Parker L, Junn J, and Kendall, A. (2005). Flexible filamentous virus structures from fiber diffraction. Fiber Diffraction Review 13, 38-42
1. Parker L, Kendall A, and Stubbs, G. (2002). Surface Features of Potato Virus X from Fiber Diffraction. Virology 300, 291-29 (featured on cover)
28. 28. Wallace NS, Gadbery JE, Cohen CI, Kendall AK, and Jackson LP. Tepsin binds LC3B to promote ATG9A trafficking and delivery. Molecular Biology of the Cell 2024 Feb 21:mbcE23090359T. doi: 10.1091/mbc.E23-09-0359-T.
27. Xie B, Guillem C, Date SS, Jung C, Kendall AK, Best J, Graham TR, and Jackson LP. An interaction between b’eta-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling. J Cell Biology 2023 Apr 3;222(4):e202008061.
26. Pembridge O, Wallace NS, Clements TP, Jackson LP. AP-4 loss in CRISPR-edited zebrafish affects early embryo development. Adv Biol Regul. 2023 Jan;87:100945
25. Kendall AK, Chandra M, Xie B, Wan W, and Jackson LP. Improved retromer cryo-EM structures reveal a new assembly interface. In revision. J Biological Chemistry 2022 Nov;298(11):102523.
24. Date SS, Xu P, Hepowit NL, Diab NS, Best J, Xie B, Jiale Du, Strieter ER, Jackson LP, MacGurn JA, Graham TR. Ubiquitination drives COPI priming and Golgi SNARE localization. eLife. 2022 Jul 29;11:e80911.
23. Chandra M, Collins BM, and Jackson LP. Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus. (2022). Advances in Biological Regulation 83:100842.
22. Kai-En Chen, Qian Guo, Yi Cui, Amy K. Kendall, Joanna Sacharz, Timothy A. Hill, Ryan J. Hall, Suzanne J. Norwood, Natalya Leneva, Boyang Xie, Zhe Yang, Rajesh Ghai, Hiroaki Suga, David Fairlie, David A. Stroud, Jackson LP, Rohan D. Teasdale, Toby Passioura, Brett M. Collins. (2020). De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex. Science Advances, 2021 Dec 3;7(49):eabg4007.
21. Chandra M†, Kendall AK, and Jackson LP†. (2021). Toward understanding the molecular role of SNX27/retromer in human health and disease. Frontiers Cell & Developmental Biology 9:642378. (†corresponding authors)
20. Xie B, Jung C, Chandra M, Engel A, Kendall AK, and Jackson LP. (2021). The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats. Advances in Biological Regulation 79:100781.
19. Snider CE, Chandra M, McDonald NA, Willet WH, Collier SE, Ohi MD, Jackson LP, and Gould KL. (2020). Opposite faces of the Cdc15 F-BAR domain create a membrane platform that coordinates cytoskeletal and signaling components during cytokinesis. Cell Reports 33 (12): 108526.
19. Crawley-Snowdon H, Yang J-C, Zaccai NR, Davis L, Wartosch L, Herman EK, Bright NA, Swarbrick JS, Collins BM, Jackson LP, Seaman MNJS, Luzio JP, Dacks JB†, Neuhaus D†, Owen DJ†. (2020). Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. Nature Communications. 11(1): 5031. (†joint corresponding authors)
18. Chandra M, Kendall AK, and Jackson LP. (2020). Unveiling the cryo-EM structure of Retromer. Biochemical Society Transactions 48 (5): 2261-72.
17. Gadbery JE*, Abraham A*, Needle C, Moth C, Sheehan J, Capra JA, Jackson LP. (2020). Integrating Structural and Evolutionary Data to Interpret Genetic Variation and Pathogenicity in Adaptor Protein Complex 4 (AP-4). Protein Sci 29 (6): 1535-1549. (*joint first authors)
16. Kendall AK, Xie B, Xu P, Wang J, Burcham R, Frazier MN, Binshtein E, Wei H, Graham TR, Nakagawa T, Jackson LP. (2020). Mammalian retromer is an adaptable scaffold for cargo sorting from endosomes. Structure 28: 393-405. (Featured on cover and in Preview article.)
15. Davies AK, Itzhak DN, Edgar JR, Archuleta TL, Hirst J, Jackson LP, Robinson MS, and Borner GHH. (2018). AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. Nature Comm 9: 3958.
14. Xu P, Hankins HM, Macdonald C, Erlinger SJ, Frazier MN, Diab NS, Piper RC, Jackson LP, MacGurn JA, and Graham TR. (2017). COPI mediates recycling of an exocytic SNARE from endosomes by recognition of a ubiquitin sorting signal. eLife 2017; 6:e28342. DOI:10.7554/eLife.28342.
13. Archuleta TA, Frazier MN, Monken A, Kendall AK, Harp J, McCoy AJ, Creanza N, and Jackson LP. (2017). Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin. Traffic 18: 590-603.
12. Frazier MN and Jackson LP. (2017). Watching real-time endocytosis in living cells. J Cell Biology 216, 9-11.
11. Frazier MN, Davies AK, Voehler M, Kendall AK, Borner GH, Chazin WJ, Robinson MS, and Jackson LP. (2016). Molecular basis for the interaction between Adaptor Protein Complex 4 (AP4) b4 and its accessory protein, tepsin. Traffic 17, 400-415.
10. Jackson LP. (2014). Structure and mechanism of COPI vesicle biogenesis. Curr Opin Cell Biol 29C, 67-73.
Postdoctoral, graduate, & undergraduate work
9. Hesketh GG*, Pérez-Dorado I*, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MN, Luzio JP, Owen DJ. (2014). VARP is Recruited Onto Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface. Dev Cell 29, 591-606. (*joint first authors)
8. Jackson LP†, Lewis M, Kent HM, Edeling MA, Evans PR, Duden R, and Owen DJ†. (2012). Molecular basis for recognition of dilysine trafficking motifs by COPI. Dev Cell 23, 1-8. (†corresponding authors)
7. Jackson LP†, Kümmel D†, Reinisch K, and Owen DJ. (2012). Structures and mechanisms of vesicle coat components and multisubunit tethering complexes. Curr Opin Cell Biol 24, 475-483. (†corresponding authors)
6. Borner GHH, Antrobus R, Hirst J, Bhumbra GS, Kozik P, Jackson LP, Sahlender DA, and Robinson MS. (2012). Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles. J Cell Biol 197, 141-60.
5. Jackson LP*, Kelly BT*, McCoy, AJ, Gaffry, T, James LC, Collins BM, Höning S, Evans PR, Owen DJ. (2010). A large scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex. Cell 141, 1220-29. (*joint first authors)
4. Pryor PR, Jackson LP, Gray SR, Edeling MA, Thompson A, Sanderson CM, Evans PR, Owen DJ, Luzio JP. (2008). Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb. Cell 134, 817-27.
3. Parker L, Kendall A, Berger, PH, Shiel, PJ, and Stubbs, G. (2005). Wheat streak mosaic virus— Structural parameters for a Potyvirus. Virology 340, 64-69 (featured on cover)
2. Stubbs G, Parker L, Junn J, and Kendall, A. (2005). Flexible filamentous virus structures from fiber diffraction. Fiber Diffraction Review 13, 38-42
1. Parker L, Kendall A, and Stubbs, G. (2002). Surface Features of Potato Virus X from Fiber Diffraction. Virology 300, 291-29 (featured on cover)
