Alex Davies's beautiful work on the proteomics of AP4 coated vesicles is out on Bioarxiv today. We're delighted to continue our collaboration with Alex, Scottie, and Georg!
Check it out here
The Jackson Lab is actively recruiting excellent and motivated graduate students for high impact projects that span structural biology, cell biology, and biochemistry of membrane trafficking proteins. Send Lauren an email if you're interested in any of the following options for next year.
* CryoEM. We have a trafficking coat protein complex in ice, and we're already at 13A! Great opportunity to learn to prepare samples, collect and analyze data, and build models.
* Crystallization/crystallography projects. We have confirmed several new binding partners for our trafficking proteins, so we are ready to undertake crystal trials.
* Biophysics & biochemistry. Multiple opportunities to learn how to use calorimetry (ITC) to quantify binding affinities and structure-based mutagenesis to test binding interfaces.
* Microscopy projects in the Nikon Center. Great chance to work with graduate student to use our excellent imaging facilities.