Rotation projects 2022-23

Please get in touch with Lauren if you are interested in rotating. The lab is a great place to train. We have an awesome lab manager (Amy), an experienced research assistant professor (Mintu), and two talented graduate students (Natalie & Cameron) to support you. We use a variety of techniques and approaches to answer fundamental questions about cell biology and human brain disease. We have multiple projects focused around important human protein complexes (retromer & sorting nexins, AP4, COPI). Options include:

1. Protein expression & purification (bacteria & mammalian cells)
2. Biochemistry: pulldown assays & calorimetry
3. Crystallization & X-ray crystallography, including small molecules/drugs
4. Single particle cryo-EM and cryo-ET
5. Imaging
6. Computational projects (AlphaFold modeling)

If you’re interested, please email your resume/CV and brief background summary (science courses, research interests) to Lauren. We’ll then set up a time to meet. We look forward to hearing from you!